• Research Questions

    • What is the connection between adult hippocampal neurogenesis and behavior?

    • How adult hippocampal neurogenesis is affected in neurobehavioral disorders?

    • What are the molecular ques regulating adult neurogenesis, self-renewal, differentiation and maturation?

    • How the immune system, and in particularly T-cells and macrophages affect neurogenesis and behavior?

    • How can mesenchymal stem cell (MSC) transplantation either locally or systemically affect adult hippocampal neurogenesis? What are the molecular and cellular mechanisms that are involved?

    • Can MSC transplantation be of therapeutic benefits for neurobehavioral disorders such as autism  spectrum disorders and schizophrenia?

    • Do neurobehavioral disorders share common pathophysiological mechanisms (epigenetics) with aging? 

  • Methodologies used

    • Immunohistochemistry

    • In vivo real-time Imaging

    • Stem transplantation

    • Behavioral Neuroscience

    • Gene expression

    • FACS

  • Keywords

    • Adult hippocampal neurogenesis, stem cells, learning and memory, T-cells, macrophages, neurobehavioral disorders, ASD, Schizophrenia

  • Head, Department of Pre-Medical Studies

  • Head, Stem cell laboratory

Phone: 972-3-937-1430

Website: http://www.ariel.ac.il/sites/gadit

Email: gadit@ariel.ac.il

© 2018 Integrative Brain Science Center - Ariel (IBSCA), Ariel University, Ariel 4070000, Israel

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